Protective effect of phenolic compounds on carbonyl-amine reactions
نویسندگان
چکیده
منابع مشابه
Highly Efficient Intramolecular Nucleophilic Reactions. The Cyclization of p-Nitrophenyl
p-Nitrophenyl N-(2-mercaptophenyl)-N-methylcarbamate cyclizes rapidly at 25' to N-methylbenzothiazolone with release of p-nitrophenol. The pH-rate constant profile is sigmoidal with pK,,, = 8.7. The effective molarity of the neighboring sulfhydryl group is 1.4 X los M in comparison with bimolecular attack of thiols on p-nitrophenyl N-methyl-Nphenylcarbamate. The pH-rate constant profile for cyc...
متن کاملAntagonism between lipid-derived reactive carbonyls and phenolic compounds in the Strecker degradation of amino acids.
The Strecker-type degradation of phenylalanine in the presence of 2-pentanal and phenolic compounds was studied to investigate possible interactions that either promote or inhibit the formation of Strecker aldehydes in food products. Phenylacetaldehyde formation was promoted by 2-pentenal and also by o- and p-diphenols, but not by m-diphenols. This is consequence of the ability of phenolic comp...
متن کاملOne-pot reductive Amination of Carbonyl Compounds using NaBH4 and Fe3O4 Magnetic Nanoparticles
One-pot reaction of aldehydes or ketons with aniline derivatives was performed using NaBH4 and Fe3O4 magnetic nanoparticles (MNPs). The optimum amount of Fe3O4 MNPs was 5 mol% under solvent free condition. The corresponding products were obtained in good to excellent yields. The magnetically recoverable iron oxide nanoparticles are found to be efficient for synthesis of amine derivatives. These...
متن کاملSOLVENT-FREE SYNTHESIS OF PYRROL DERIVATIVES USING MULTICOMPONENT REACTIONS OF 1,3-DICARBONYLS, ACTIVATED CARBONYL COMPOUNDS, AND PRIMARY ALKYLAMINES
A one-pot synthesis of pyrrole derivatives via reaction between activated carbonyl compounds, primary amines and 1,3-dicarbonyls under solvent-free conditions is described.
متن کاملProtective effects of phenolic compounds on CCl4-induced toxicity in isolated rat hepatocytes.
The protective effects of a series of phenolic compounds, phenolic acids and flavonoids on the cytotoxicity of CCl4 in rat hepatocytes were studied. A number of flavones, 7,8-dihydroxy-flavone, luteolin and hypolaetin-8-glucoside, flavonols, morin, quercetin, robinetin and gossypin, phenolic acids, gallic, caffeic and chlorogenic acids, as well as the flavane (+)-catechin significantly inhibite...
متن کامل